The ONLY purpose of the parathyroid glands is to regulate the calcium level in our bodies within a very narrow range so that the nervous and muscular systems can function properly. This is all they do. They measure the amount of calcium in the blood every minute of every day... and if the calcium levels go down a little bit, the parathyroid glands recognize it and make parathyroid hormone (PTH) which goes to the bones and takes some calcium out (makes a withdrawal from the calcium vault) and puts it into the blood. When the calcium in the blood is high enough, then the parathyroids shut down and stop making PTH.
The topic of my master’s thesis evolved not only from my own interest and fascination of jacquard weaving. A little bit of luck contributed to the final outcome of this study as well. At an early point of my study, I wanted to discuss the material and col-our design of woven textiles. I considered various ways on how to approach the subject from a fresh and meaningful point of view. In the beginning of the spring of 2014, I spent three months on an internship at the Italian weaving mill Lodetex. Lodetex is specialized in the production of jacquard fabrics for furnishing markets. I decided that doing my thesis in collaboration with Lodetex would be a viable continuum after working in the company as an intern. I discussed the matter with owner Luca Farhanghi and he agreed that a thesis collaboration would be interesting and beneficial for the both of us. He informed me about a few production lines that the company planned on developing. One of these lines related to clipped designs. To me, the development of clipped designs seemed like a fascinating and interesting topic to research. Since I had already designed two clipped designs during my internship, I realized that the weaving process of these fabrics required more advanced technical understanding in interwoven structure of cloth. Therefore, this project gave me a chance to improve my skills in artistic expression as well as develop my knowledge in designing, weaving and finishing of clipped cloths.
A total of 861 patients were randomly assigned to nab-paclitaxel plus gemcitabine (431 patients) or gemcitabine (430). The median overall survival was months in the nab-paclitaxel-gemcitabine group as compared with months in the gemcitabine group (hazard ratio for death, ; 95% confidence interval [CI], to ; P<). The survival rate was 35% in the nab-paclitaxel-gemcitabine group versus 22% in the gemcitabine group at 1 year, and 9% versus 4% at 2 years. The median progression-free survival was months in the nab-paclitaxel-gemcitabine group, as compared with months in the gemcitabine group (hazard ratio for disease progression or death, ; 95% CI, to ; P<); the response rate according to independent review was 23% versus 7% in the two groups (P<). The most common adverse events of grade 3 or higher were neutropenia (38% in the nab-paclitaxel-gemcitabine group vs. 27% in the gemcitabine group), fatigue (17% vs. 7%), and neuropathy (17% vs. 1%). Febrile neutropenia occurred in 3% versus 1% of the patients in the two groups. In the nab-paclitaxel-gemcitabine group, neuropathy of grade 3 or higher improved to grade 1 or lower in a median of 29 days.